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Research interests

The Baumann group investigates structure-function relationships in proteases, translation initiation factors and extracellular matrix components.

We are especially interested in the mechanism and substrate recognition of metalloproteases and the ATP-driven conformational changes occurring in protein degradation machines like FtsH. The group also investigates how Serpins fold collagen and explores the architecture of protein complexes involved in translation initiation. A major methodology is X-ray crystallography to visualize the atomic structure of these molecules.

Research topics: